Week 2 of the NFL season offers several promising matchups on different days of the week.
Among the most intriguing games are the Chargers and Chiefs on Thursday Night Football, the Bengals and Cowboys on Sunday and the Titans and Bills on Monday Night Football.
Here’s everything you need to know about the NFL odds for Week 2 — the point spread, moneyline and total over/under (with all NFL odds via FOX Bet).
All times ET
THURSDAY’S GAME
Los Angeles Chargers @ Kansas City Chiefs (8:20 p.m., NBC)
Point spread: No line available
Moneyline: No line available
Total scoring over/under: No line available
SUNDAY’S GAMES
New York Jets @ Cleveland Browns (1 p.m., CBS)
Point spread: Browns -6 (Browns favored to win by more than 6 points, otherwise Jets cover)
Moneyline: Browns -278 favorites to win (bet $10 to win $13.60 total); Jets +210 underdogs to win (bet $10 to win $31 total)
Total scoring over/under: 40.5 points scored by both teams combined

New York Jets
NYJ

Cleveland Browns
CLE
Washington Commanders @ Detroit Lions (1 p.m., FOX)
Point spread: Lions -2.5 (Lions favored to win by more than 2.5 points, otherwise Commanders cover)
Moneyline: Lions -138 favorites to win (bet $10 to win $17.25 total); Commanders +110 underdogs to win (bet $10 to win $21 total)
Total scoring over/under: 48.5 points scored by both teams combined

Washington Commanders
WAS

Detroit Lions
DET
Tampa Bay Buccaneers @ New Orleans Saints (1 p.m., FOX)
Point spread: Buccaneers -3 (Buccaneers favored to win by more than 3 points, otherwise Saints cover)
Moneyline: Buccaneers -167 favorites to win (bet $10 to win $15.99 total); Saints +130 underdogs to win (bet $10 to win $23 total)
Total scoring over/under: 44 points scored by both teams combined

Tampa Bay Buccaneers
TB

New Orleans Saints
NO
Carolina Panthers @ New York Giants (1 p.m., FOX)
Point spread: Giants -2.5 (Giants favored to win by more than 2.5 points, otherwise Panthers cover)
Moneyline: Giants -138 favorites to win (bet $10 to win $17.25 total); Panthers +110 underdogs to win (bet $10 to win $21 total)
Total scoring over/under: 43 points scored by both teams combined

Carolina Panthers
CAR

New York Giants
NYG
New England Patriots @ Pittsburgh Steelers (1 p.m., CBS)
Point spread: Patriots -1.5 (Patriots favored to win by more than 1.5 points, otherwise Steelers cover)
Moneyline: Patriots -120 favorites to win (bet $10 to win $18.33 total); Steelers -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring over/under: 41 points scored by both teams combined

New England Patriots
NE

Pittsburgh Steelers
PIT
Indianapolis Colts @ Jacksonville Jaguars (1 p.m., CBS)
Point spread: Colts -4 (Colts favored to win by more than 4 points, otherwise Jaguars cover)
Moneyline: Colts -213 favorites to win (bet $10 to win $14.69 total); Jaguars +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 46 points scored by both teams combined

Indianapolis Colts
IND

Jacksonville Jaguars
JAX
Miami Dolphins @ Baltimore Ravens (1 p.m., CBS)
Point spread: Ravens -3.5 (Ravens favored to win by more than 3.5 points, otherwise Dolphins cover)
Moneyline: Ravens -182 favorites to win (bet $10 to win $15.49 total); Dolphins +140 underdogs to win (bet $10 to win $24 total)
Total scoring over/under: 44 points scored by both teams combined

Miami Dolphins
MIA

Baltimore Ravens
BAL
Atlanta Falcons @ Los Angeles Rams (4:05 p.m., FOX)
Point spread: Rams -10 (Rams favored to win by more than 10 points, otherwise Falcons cover)
Moneyline: Rams -556 favorites to win (bet $10 to win $11.80 total); Falcons +375 underdogs to win (bet $10 to win $47.50 total)
Total scoring over/under: 47.5 points scored by both teams combined

Atlanta Falcons
ATL

Los Angeles Rams
LAR
Seattle Seahawks @ San Francisco 49ers (4:05 p.m., FOX)
Point spread: 49ers -9 (49ers favored to win by more than 9 points, otherwise Seahawks cover)
Moneyline: 49ers -455 favorites to win (bet $10 to win $12.20 total); Seahawks +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 42.5 points scored by both teams combined

Seattle Seahawks
SEA

San Francisco 49ers
SF
Cincinnati Bengals @ Dallas Cowboys (4:25 p.m., CBS)
Point spread: Bengals -7 (Bengals favored to win by more than 7 points, otherwise Cowboys cover)
Moneyline: Bengals favorites -303 to win (bet $10 to win $13.30 total); Cowboys +225 underdogs to win (bet $10 to win $32.50 total)
Total scoring over/under: 43.5 points scored by both teams combined

Cincinnati Bengals
CIN

Dallas Cowboys
DAL
Houston Texans @ Denver Broncos (4:25 p.m., CBS)
Point spread: Broncos -11 (Broncos favored to win by more than 11 points, otherwise Texans cover)
Moneyline: Broncos -556 favorites to win (bet $10 to win $11.80 total); Texans +375 underdogs to win (bet $10 to win $47.50 total)
Total scoring over/under: 44 points scored by both teams combined

Houston Texans
HOU

Denver Broncos
DEN
Arizona Cardinals @ Las Vegas Raiders (4:25 p.m., CBS)
Point spread: Raiders -5.5 (Raiders favored to win by more than 5.5 points, otherwise Cardinals cover)
Moneyline: Raiders -278 favorites to win (bet $10 to win $13.60 total); Cardinals +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 51.5 points scored by both teams combined

Arizona Cardinals
ARI

Las Vegas Raiders
LV
Chicago Bears @ Green Bay Packers (8:20 p.m., NBC)
Point spread: Packers -10 (Packers favored to win by more than 910 points, otherwise Bears cover)
Moneyline: Packers -500 favorites to win (bet $10 to win $12 total); Bears +300 underdogs to win (bet $10 to win $40 total)
Total scoring over/under: 43 points scored by both teams combined

Chicago Bears
CHI

Green Bay Packers
GB
MONDAY’S GAMES
Tennessee Titans @ Buffalo Bills (7:15 p.m., ESPN)
Point spread: Bills -10 (Bills favored to win by more than 10 points, otherwise Titans cover)
Moneyline: Bills -455 favorites to win (bet $10 to win $12.20 total); Titans +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 49.5 points scored by both teams combined

Tennessee Titans
TEN

Buffalo Bills
BUF
Vikings @ Eagles (8:30 p.m. ET, ABC)
Point spread: Eagles -1.5 (Eagles favored to win by more than 1.5 points, otherwise Vikings cover)
Moneyline: Eagles -125 favorites to win (bet $10 to win $18 total); Vikings +100 underdogs to win (bet $10 to win $20 total)
Total scoring over/under: 51.5 points scored by both teams combined

Minnesota Vikings
MIN

Philadelphia Eagles
PHI
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